Office of Diversion Control, US Department of Justice, Drug Enforcement Administration

RESOURCES > Electronic Commerce Initiatives

Electronic Commerce Initiatives

CSOS (Controlled Substances Ordering System)

DEA's Controlled Substance Ordering System allows for electronic orders of controlled substances without the supporting paper form DEA-222. All current information regarding CSOS is available on

Economic Impact Analysis (2005) (PDF)

CSOS Archived Material

Notice of Intent To Conduct Performance Verification Testing of Public Key Infrastructure Enabled Controlled Substance Orders

Electronic Prescriptions for Controlled Substances (EPCS)

Federal Register Notices

Third Party Reviews of Prescriber or Pharmacy EPCS Applications

Outreach, Questions and Answers

Historical documents

Public meetings

Emergency Disaster Relief
Got Drugs? Turn in your unused or expired medication for safe disposal here.
Alert! Extortion Scam

Office of Diversion Control  •  8701 Morrissette Drive  •  Springfield, VA 22152  •  1-800-882-9539