Office of Diversion Control, US Department of Justice, Drug Enforcement Administration



Renewal Applications Online

DEA Form 224a – Retail Pharmacy, Hospital/Clinic, Practitioner, Teaching Institution, or Mid-Level Practitioner
DEA Form 225a – Manufacturer, Distributor, Researcher, Analytical Laboratory, Importer, Exporter
DEA Form 363a – Narcotic Treatment Programs
DEA Form 510a – Domestic Chemical

New Applications Online

DEA Form 224 – Retail Pharmacy, Hospital/Clinic, Practitioner, Teaching Institution, or Mid-Level Practitioner
DEA Form 225 – Manufacturer, Distributor, Researcher, Canine Handler, Analytical Laboratory, Importer, Exporter
DEA Form 363 – Narcotic Treatment Programs
DEA Form 510 – Domestic Chemical

To Apply for New Applications for Registration through the U.S. Postal Service

Researcher - Schedule I Only

Researchers with Schedule I drugs only must submit DEA 225 PDF application and the protocol found in 21 CFR 1301.18. You cannot apply online for your initial application.

Registration Tools

Chain Renewals

Duplicate Certificates

This form is not for change of address or matters pertaining to the renewal of your registration. For these matters call 1-800-882-9539; for change of address, use the Address Changes Form.

Duplicate Receipt of Registration Application

Online Pharmacy Modifications

  • Modify business activity from Retail Pharmacy to Retail Online Pharmacy
  • Modify business activity from Retail Online Pharmacy to Retail Pharmacy
  • Modify existing Retail Online Pharmacy Information

Official Order Forms

NOTICE: Modification to the "Mailing Address" section of the DEA Form 222

Large Volume Order Forms (DEA Form 222)

Q & A - DEA Form 222 - Official Order Forms

Registration Changes - Use for the following Registration Changes:

Name Changes | Schedule Changes | Drug Code Changes | Address Changes - Do not submit this until you have an approved state license for the new address. Please note that these changes will become effective immediately upon DEA approval.

Registration for Disposal of Controlled Substances

  • Modify eligible DEA registration to collect pharmaceutical controlled substances from ultimate users (e.g., patients)
  • Modify DEA registration to stop being a collector
  • Modify existing collector registration information

Search for an Authorized Collector Location

Registration Validation

Registration Resources

Registration Procedures

Registration Categories and Fees

Customer Service Plan for Registrants (January 2010)

Pharmacist's Manual

Practitioner's Manual

Practitioner's License Requirements

Mid-Level Practitioners (MLP) Authorization by State

Questions & Answers

Reinstated and Retired Registrant List

A complete listing of all active DEA registration numbers can be obtained from the U.S. Department of Commerce National Technical Information Service (NTIS) Web Site at For your convenience and the most accurate information of a Registrant's status, please use the Registration Validation Tool. For further information, contact

Registrant Population (Active)

Summary | Active Registrants by State | Active Registrants by Business Activity | Active Chemical Handler Registrants

State Licensing Boards

2012 Fee Rule

Controlled Substances and List I Chemical Registration and Reregistration Fees (March 15, 2012)

Supporting and Related Material:

New Registrant Fee Schedule Calculations - Diversion Control Fee Account (PDF) (March 12, 2012)

ECONOMIC IMPACT ANALYSIS of Final Rule on Controlled Substances and List I Chemical Registration and Reregistration Fees, DEA-346 (PDF) (March 12, 2012)

DEA Registrant Letter (PDF) (March 12, 2012)

Registration Fees Fact Sheet (PDF) (March 12, 2012)

New DEA Number Series

DEA is announcing that, effective immediately, DOD personal service contractors will be issued a new DEA registration number that begins with the letter "G". This new first character will be in addition to the current first characters A, B, F of the DEA registration for practitioners. The G series DEA registration number will be listed in the database provided to NTIS and available on the DEA website validation query system.

Registrant type (first letter of DEA Number):

A/B/F/G – Hospital/Clinic/Practitioner/Teaching Institution/Pharmacy

M – Mid-Level Practitioner (NP/PA/OD/ET, etc.)

P/R – Manufacturer/Distributor/Researcher/Analytical Lab/Importer/Exporter/Reverse Distributor/Narcotic Treatment Program

Registration Help

Contact DEA Registration Service Center at 1-800-882-9539

Email - Be sure to include your DEA Registration number in your email

Locate Field Office Registration Program Specialist


CMEA (Combat Meth Epidemic Act)

CMEA Required Training & Self-Certification

Quota Applications

Emergency Disaster Relief
Got Drugs? Turn in your unused or expired medication for safe disposal here.
Alert! Extortion Scam

Office of Diversion Control  •  8701 Morrissette Drive  •  Springfield, VA 22152  •  1-800-882-9539